Durezol

Generic Name: difluprednate ophthalmic (DYE floo PRED nate off THAL mik)
Brand Names: Durezol

What is Durezol?

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Durezol is a steroid medicine. It prevents the release of substances in the body that cause inflammation.

Durezol is used to treat eye swelling caused by surgery.

Durezol may also be used for other purposes not listed in this medication guide.

Important information about Durezol

You should not use Durezol if you are allergic to difluprednate, or if you have any type of viral or fungal eye infection, ocular herpes, or an untreated infection in your eye or elsewhere, including chickenpox.

Before using Durezol, tell your doctor if you are allergic to any drugs, or if you have herpes. You may need a dose adjustment or special tests to safely use Durezol.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not stop using Durezol suddenly without first talking to your doctor. Tell your doctor if your symptoms do not improve after 2 days of treatment with Durezol.

Do not wear any contact lens that has not been approved by your doctor. Do not use Durezol while you are wearing regular contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses and cause discoloration. Wait at least 15 minutes after using Durezol before putting your contact lenses in.

Do not use any other eye medications unless your doctor has prescribed them.

Before using Durezol

You should not use Durezol if you are allergic to difluprednate, or if you have any type of infection, especially:

a fungal or bacterial eye infection;
any type of viral eye infection, such as ocular herpes; or
an untreated infection in your eye or elsewhere, including chickenpox.

Before using Durezol, tell your doctor if you are allergic to any drugs, or if you have herpes. You may need a dose adjustment or special tests to safely use Durezol.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Durezol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Durezol?

Use Durezol exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Durezol is usually given 4 times per day beginning 24 hours after your surgery and continuing for 2 weeks. After the first 2 weeks, your dose may be decreased to 2 times per day for 1 week or longer. Follow your doctor's instructions.

Wash your hands before using the eye drops.

To apply the eye drops:

Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.
Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.
Use the eye drops only in the eye you are having surgery on.
Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Tell your doctor if your symptoms do not improve after 2 days of treatment with Durezol. Do not stop using Durezol suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is not causing harmful effects, your eyes may need to be checked on a regular basis. Do not miss any scheduled visits to your doctor.

Store this medication at room temperature away from heat, moisture, and light. Do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use Durezol as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of Durezol is not likely to cause life-threatening symptoms.

What should I avoid after I receive Durezol?

Do not wear any contact lens that has not been approved by your doctor.

Do not use Durezol while you are wearing regular contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses and cause discoloration. Wait at least 15 minutes after using Durezol before putting your contact lenses in.

Do not use any other eye medications unless your doctor has prescribed them.

Durezol can cause side effects that may impair your vision. Be careful if you drive or do anything that requires you to see clearly.

Durezol side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

pain behind your eyes, sudden vision changes, severe headache;
sudden eye irritation;
blurred vision, tunnel vision, eye pain, or seeing halos around lights; or
signs of new eye infection, such as swelling, draining, or crusting of your eyes.

Less serious side effects may include mild burning, stinging, or itching of your eyes.

feeling like something is in your eye;
eyes being more sensitive to light;
eye pain, itching, or redness; or
itchy or watery eyes.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Durezol?

It is not likely that other drugs you take orally or inject will have an effect on Durezol used in the eyes. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about Durezol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.