Dextromethorphan and triprolidine

Generic name: dextromethorphan and triprolidine [ DEX-troe-meth-OR-fan-and-trye-PROE-li-deen- ]
Brand name: Endal Liquid
Dosage form: oral liquid (10 mg-1.25 mg/5 mL)
Drug class: Upper respiratory combinations

Medically reviewed by Drugs.com on Nov 16, 2023. Written by Cerner Multum.

What is dextromethorphan and triprolidine?

Dextromethorphan and triprolidine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

Dextromethorphan and triprolidine may also be used for purposes not listed in this medication guide.

Dextromethorphan and triprolidine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

dextromethorphan and triprolidine may cause serious side effects. Stop using dextromethorphan and triprolidine and call your doctor at once if you have:

• dizziness;

• nervousness; or

• sleep problems (insomnia).

Common side effects of dextromethorphan and triprolidine may include:

• drowsiness;

• constipation; or

• feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Do not use this medicine if you are using or if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Before taking this medicine

Do not use dextromethorphan and triprolidine if you are using or if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

• asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

• high blood pressure, heart disease;

• glaucoma;

• diabetes;

• urination problems due to an enlarged prostate; or

• a thyroid disorder.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

How should I take dextromethorphan and triprolidine?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use.

Do not give this medicine to a child without medical advice. Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

dextromethorphan and triprolidine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking dextromethorphan and triprolidine?

Drinking alcohol with dextromethorphan and triprolidine can cause side effects.

Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

What other drugs will affect dextromethorphan and triprolidine?

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 1.01.